by Anne Eglash MD, IBCLC, FABM
What are the safest pain medications to take during breastfeeding? Lately, the media has been raising awareness of the opiate crisis in our country, with thousands of people dying from overdosing on heroin, prescription narcotics, and other illicit substances. The authors of a recent update on pain management for women published in the American Journal of OB/Gyn point out that opiate prescribing has skyrocketed in the USA since 2001, when hospitals were expected to measure pain as a ‘vital sign’. This has led to more aggressive treatment of pain using narcotics.
Breastfeeding women are often given narcotics for their postpartum pain, and for other medical/post-operative pain during the course of lactation. The purpose of this recent update is to highlight non-narcotic options and the safest narcotic options to treat pain during lactation.
According to these authors, what do you believe are true statements regarding the use of pain medication during lactation? Chose 1 or more:
- The only safe anti-inflammatory (NSAID) medication during lactation is ibuprofen.
- Anti-inflammatory medications should be avoided if the infant has a heart condition that depends on a patent ductus arteriosus.
- Low doses of morphine have the lowest transmission into breastmilk, as compared to other opiates.
- Oxycodone is preferred over hydrocodone because hydrocodone causes too much infant sedation.
- Codeine should be avoided in breastfeeding women because some mothers and infants are ultrafast metabolizers, at risk for respiratory depression from this.
- The USA consumes the highest amounts of opiates, accounting for 99.7% of hydrocodone use globally.
See the Answer
The correct answers are B, C, E & F
Perioperative pain management: an update for obstetrician-gynecologists
Georgine Lamvu, MD, MPH, Jessica Feranec, MD, Emily Blanton, MD
The opioid epidemic in the United States is unprecedented and continues to worsen. Many opioid abusers obtain their pills through legitimate prescriptions, directly or indirectly, from a medical provider. While practitioners have a responsibility to treat pain, it is now becoming clear that aggressive opioid prescription practices contribute to an epidemic of abuse. The medical community has to balance the unintended consequences of opioid misuse and abuse with the need to provide adequate pain control. Additionally, providers are being held accountable by the legal system and professional organizations for their prescribing practices. Responsible use of opioids is paramount and pain control does not supersede safety. Effective and safe pain management requires that providers perform risk assessments, understand medication risks, avoid excessive reliance on opioids, and adequately monitor and educate patients. Obstetricians and gynecologists are uniquely positioned to influence pain management practices as primary care and surgical clinicians who regularly manage both acute and chronic pain conditions. Therefore, the objective of this publication was to familiarize obstetricians and gynecologists with contemporary concepts in pain management and summarize recent guidelines in a manner that is applicable to our specialty. We focus on perioperative pain management, which is the time period immediately before, during, and after surgery. Topics reviewed include proper risk assessment to evaluate a patient’s potential for poor pain control or development of chronic pain or misuse of opioids; multimodal pain management with nonpharmacological, nonopioid alternatives, safe opioid-use strategies; education and documentation; and special considerations for women, veterans, and lactation concerns.
Milk Mob Comment by Anne Eglash MD, IBCLC, FABM
The first task at hand is to not use opiates as first line medications for pain. Most breastfeeding dyads should be able to tolerate anti-inflammatory medications such as ibuprofen, naproxen, or ketorolac, at least short term. Mothers with very high blood pressure, history of stomach ulcers, kidney failure, or infants who have a heart condition dependent on a patent ductus arteriosus should not take anti-inflammatories.
The safest narcotics for a breastfeeding dyad are low dose morphine and hydrocodone (Vicodin). Morphine has low transmission into breastmilk, while hydrocodone has a very low risk of infant sedation. Oxycodone (Percocet) has a similar risk as codeine for respiratory depression among ultrafast metabolizers, so should be avoided. Oxycodone has been documented to cause nerve system depression in 20% of infants exposed during breastfeeding.
Approximately 1/3-1/2 of all controlled substance overdoses in the USA involve the combination of narcotics and benzodiazepines, such as diazepam (Valium) and lorazepam (Ativan). Therefore, the combination of narcotics and benzodiazepines should be avoided or greatly limited.
Sally Hammerman
Excellent information for those of us who work/consult with breastfeeding women. Although we may not have the ability to prescribe, we do have the ability to observe and comment.
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